OPS works closely with the National Association of Pipeline Safety Representatives (NAPSR) and the National Association of Regulatory Utility Commissioners (NARUC). NAPSR is an affiliation of state program managers who are certified by OPS to administer the state pipeline safety programs. Each year, NAPSR holds national and regional meetings to promote information exchange on pipeline technology, inspection techniques, operational problems, significant accidents, and innovative approaches for strengthening the pipeline safety program. NAPSR, on an annual basis, submits resolutions on a variety of pipeline safety concerns of national scope for OPS consideration.

NARUC is an organization of governmental agencies committed to improving the quality and effectiveness of utility regulation in America. The Staff Subcommittee on Pipeline Safety under NARUC's Committee on Gas addresses specific pipeline safety issues.