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49 CFR part 199 (PHMSA drug and alcohol testing regulation) and 49 CFR part 40 (DOT drug and alcohol testing regulation) require operators to conduct drug and alcohol testing of covered employees who perform operation, maintenance, or emergency-response functions regulated by 49 CFR part 192, 193, or 195.

Covered functions performed on master meter systems, as defined in section 191.3, and pipeline systems that transport only petroleum gas or petroleum gas/air mixtures are excluded from testing conducted under PHMSA and DOT drug and alcohol regulations.

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